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Life Science Zurich Communication & Events

Immunotherapy Reduces Lung and Liver Fibrosis in Mice

Image Lung Tissue
Healthy lung tissue contains many air-filled alveoli, in which oxygen is absorbed from the respiratory air into the blood (left). In fibrotic lung tissue, these have been displaced by connective tissue growths (right). (Image: Christian Stockmann, UZH)

Chronic diseases often lead to fibrosis, a condition in which organ tissue suffers from excessive scarring. Researchers at the University of Zurich have now developed an immunotherapy that specifically targets the cause – activated fibroblasts – while leaving normal connective tissue cells unharmed. If this approach is also found to work in humans, it could lead to an effective treatment for fibrosis.

UZH News