Detailed view of a molecular toxin transporter

The transport protein ABCG2 (centre) is embedded in the cell membrane. It recognises over 200 substances in the cell interior (below) and transports them outside (above). (Visualisations: ETH Zurich / Scott Jackson, Ioannis Manolaridis, Kaspar Locher)

Transport proteins in the cells of our body protect us from particular toxins. Researchers at ETH Zurich and the University of Basel have now determined the high-resolution three-dimensional structure of a major human transport protein. In the long term, this could help to develop new medications. ETH-News