Protein shapes indicate Parkinson’s disease

Image Brain
To date, Parkinson's disease can only be detected when it becomes apparent through symptoms. (Photograph: Keystone / Science Photo Library)

ETH Zurich researchers have found that a set of proteins have different shapes in the spinal fluid of healthy individuals and Parkinson’s patients. These could be used in the future as a new type of biomarker for this disease. 

Many human diseases can be detected and diagnosed using biomarkers in blood or other body fluids. Parkinson’s disease is different: to date, there is no such biomarker being used in the clinicto indicate this neurodegenerative disease.

A team led by ETH Zurich Professor Paola Picotti could now help to close this gap. In a study just published in the journal Nature Structural and Molecular Biology, the researchers present 76 proteins that might serve as biomarkers for the detection of Parkinson’s disease.

ETH News

Silvie Cuperus