Immunotherapy Reduces Lung and Liver Fibrosis in Mice

Image Lung Tissue
Healthy lung tissue contains many air-filled alveoli, in which oxygen is absorbed from the respiratory air into the blood (left). In fibrotic lung tissue, these have been displaced by connective tissue growths (right). (Image: Christian Stockmann, UZH)

Chronic diseases often lead to fibrosis, a condition in which organ tissue suffers from excessive scarring. Researchers at the University of Zurich have now developed an immunotherapy that specifically targets the cause – activated fibroblasts – while leaving normal connective tissue cells unharmed. If this approach is also found to work in humans, it could lead to an effective treatment for fibrosis.

UZH News

Silvie Cuperus

News